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Brand: centoria.fr
SKU: 29660745339
Price: 22.90 USD
Availability: InStock
Rating: 4.2646 (18 reviews)

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SKU: 29660745339 · From centoria.fr

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Description

A striking selectivity for AR binding sites based on the presence of adjacent binding motifs emerged in studies in which SUMO2 and 3 activity was inhibited pharmacologically: SUMOylation inhibition using ML-792 inhibited AR binding to genomic regions that contain multiple AREs, but enhanced AR binding to less accessible AREs that are enriched for pioneering transcription factor binding sites