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10.1530/JOE-16-0035 2 AmatoA.BaldassanoS.SerioR.MulF

Mild sonication may be used if needed

SCE was induced by acetaldehyde (1.3-106 g/ml) in the absence of exogenous metabolic activation in Chinese hamster ovary cells and human lymphocyte cultures (Obe & Ristow, 1977

Subsequently, a 1-year clinical trial was also conducted, and the results showed that probiotics slowed down the decline of kidney function in individuals with stages 35 CKD, both acute and chronic kidney injuries (106)