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doi: 10.3978/j.issn.2304-3881.2014.11.01

We grew up hearing about it for immunity, for fighting colds, and later, for brightening the skin

Arch Gen Psychiatry

Substance P may stimulate the phosphorylation of p70 S6K1 and inhibit the phosphorylation of p38 MAPK by activating the NK-1R receptor, thereby inhibiting TRP1 by MITF, thus playing an anti-melanin synthesis role (Ping et al., 2012)