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First, that individual differences in DNA sequence in genes for intrinsic factor, the intestinal receptor complex, the circulating carrier proteins, the cellular uptake receptor, and the intracellular processing enzymes measurably alter circulating B12 and its active fraction

Peptides and their fragments play roles across multiple domains of metabolic communication, neurotransmission, and both general and highly specific signaling pathways

The committee reviews the specific use each was nominated for, hears from nominators, and votes a recommendation which is non-binding

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