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10.1016/j.neuroscience.2014.11.025 26

This suggests that the experimental variables substantially impact the assay outcomes

doi: 10.3389/fnut.2024.1499697 106 ZhangFXuHXiaRYuPLiYYuXet al

However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007