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Specifically, superoxide anion and hydroxyl radicals, also known as free radicals, are strongly oxidative due to the existence of one or more unpaired free electrons in their outer electron orbitals, therefore easily grabbing electrons from other substances and predisposing to free radical chain reactions, which causes immense damage to DNA, proteins, and lipids ( ROS production has been unravelled to play a critical role in the pathogenesis of RA by directly or indirectly inducing the participation of relevant cells in the pathogenesis of RA ( 2 -, inhibit the synthesis of matrix components such as proteoglycans by chondrocytes and damage the extracellular matrix through activation and up-regulation of matrix metalloproteinases, leading to cartilage damage ( 3.3 Abnormal energy metabolism Cells in living organisms acquire energy from sugars, as do chondrocytes, which obtain energy through two major metabolic pathways, namely glycolysis and the Krebs cycle

Interdisciplinary collaboration will be key to supporting reproducible results, spanning the fields of genetics, neurosurgery, and pharmacology, alongside radiation oncology

150iu Bottles: Mix 1.5mL (150 units) of cold bacteriostatic water into powder