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Liver transplantation in an infant with cerebrotendinous xanthomatosis, cholestasis, and rapid evolution of liver failure

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In animal studies, it affects angiogenesis (blood vessel formation), collagen organization, and growth factor modulation through pathways including EGR-1 gene upregulation

But see your doctor if: This is the first time you've had an outbreak You have a weakened immune system, for instance, because you have HIV or are taking immune suppressive drugs Your sores don't heal within 2 weeks Your symptoms are severe or so painful that you have trouble eating or drinking You have outbreaks often You have gritty or painful eyes Oral Herpes Tests Your doctor may be able to diagnose oral herpes based on where your blisters are and what they look like on a physical examination