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[33] It does that by increasing the rate at which cells burn fat via a messenger molecule called CAMP and reducing the level of glucose by improving insulin sensitivity

Preclinical and early human data suggest it may promote lipolysis, inhibit lipogenesis, and preferentially act on adipose tissue by influencing beta3 adrenergicmediated pathways and hormonesensitive lipase activity

Notably, the highest dose tested (54 mg) showed increased gastrointestinal event frequency compared to lower doses, suggesting a dose-relationship for this effect category

Vitamin B12 deficiency is defined as a serum vitamin B12 level of less than 150 pmol/L