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About 7% of patients using tretinoin 0.02%, compared to less than 1% of the control patients, had sufficiently severe local irritation to warrant short-term use of mild topical corticosteroids to alleviate local irritation

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Therefore, avidin can be used to selectively mask free biotin in cell lysates or cell culture supernatants, whereas the Strep-tagII or Twin-Strep-tag at the target protein remain accessible

Larger vials suit experienced researchers with established protocols who know exactly how much they'll use over extended periods