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data show that 24.3% of adults reported chronic pain in 2023, and 8.5% experienced high-impact chronic painpain that frequently limits daily or work activitiesreflecting a worsening trend and emphasizing the need for more personalized and integrated therapeutic approaches (36)

Inflammation-induced mucosal damage and ulceration reduce the absorptive surface area, leading to malabsorption even in the absence of surgical intervention

[DOI] [PMC free article] [PubMed] [Google Scholar] 363.Simic, P