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In an in vitro PE model, grape juice intake appears to have a different effect than resveratrol supplementation alone, suggesting that other bioactive molecules in grape juice combined with SIRT1-eNOS-NO have therapeutic potential in PE (116)

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At the transport level, lactate achieves dynamic intracellular-extracellular and intercellular exchange through the MCT family (such as MCT1 and MCT4), a process mediated by factors such as pH, lactate concentration gradients, and cellular redox reactions [70]