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Description

Characteristics and outcome of exertional heatstroke patients complicated by acute hepatic injury: a cohort study

(2019) 3:e165

Importantly, mitochondrial content was restored when HIF1 or HIF2 were simultaneously inactivated with Vhl , demonstrating that loss of mitochondrial abundance in Vhl -deficient renal epithelium can be entirely attributed to the overactivation of both HIF1 and HIF2 isoforms (Farsijani et al., 2016)