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Systematic review and meta-analysis of 29 trials investigating NAC use in cardiac surgery, finding significantly reduced incidence of both atrial fibrillation (odds ratio 0.5) and acute kidney injury (odds ratio 0.7)

Clark HL, Jhingran A, Sun Y, Vareechon C, de Jesus Carrion S, Skaar EP, Chazin WJ, Calera JA, Hohl TM, Pearlman E: Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits ExtracellularAspergillus fumigatusHyphal Growth and Corneal Infection .J Immunol2016, 196:336-344 57

Symptoms typically begin within two to four days and include insomnia, nausea, flu-like symptoms, dizziness, and irritability

The type 1 equilibrative nucleoside transporter regulates ethanol intoxication and preference