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Complementary Strategies for Joint Health AOD-9604 works best as part of a thorough joint health approach: Resistance training: Strengthening the muscles around a joint reduces mechanical stress on the cartilage and provides dynamic stability Maintaining healthy body weight: Every pound of body weight translates to approximately 4 pounds of force across the knee joint during walking

bmjopen.bmj.comHH Phan, Nguyen ATT (2025) MD DoBMJ open, 2025bmjopen.bmj.com 15:100672 Sato Y, Ouchi K, Funase Y, Yamauchi K, Aizawa T Relationship between metformin use, vitamin B12 deficiency, hyperhomocysteinemia and vascular complications in patients with type 2 diabetes

In real care, the safest rule is simple: do not mix therapies without a clinician who can track side effects and labs

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