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Conventional treatments (compression, sclerotherapy, ablation, surgery) manage hemodynamic dysfunction by reducing venous reflux or removing damaged veins entirely they dont restore vein wall collagen, repair endothelial damage, or reverse the cellular pathology that caused varicose veins

This can cause methyl trapping, where the excess methylfolate is unable to be utilised in the methionine cycle (through the MTR enzyme) as usable B12 levels are too low

General information:Vitamin B complex injection is a sterile solution for intramuscular or slow intravenous injection composed of vitamins that can be classified as belonging to the vitamin B complex group

Some patients anecdotally report altered responses to alcohol while taking these medications, though individual experiences vary considerably