selenium supplementation glutathione peroxidase The opposing activity of supplemental antioxidants and and Mechanism of glutathione peroxidase (GPx)

doi: 10.1016/j.jconrel.2021.11.019 [DOI] [PubMed] [Google Scholar] 135.Lei Z, Xiang C, Pingqiang C, Pingqiang C, Han S

HIF-1 can directly bind to and activate the promoter region of the NLRP3 gene, thereby increasing the substrate pool for inflammasome assembly

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Because there is no physiological way for excess iron to be actively excreted, iron accumulation within tissues causes progressive organ damage that can be fatal without chelation therapy [21]