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LIMA1: A newly identified player in the field of cholesterol control

HeinsenFAKnechtHNeulingerSCSchmitzRAKnechtCKuhbacherTet al

Research has indicated that genetic variations to the T allele of the C677T MTHFR gene have been associated with increased risk of hyperhomocysteinemia

Microscopic analysis revealed enhanced ROS generation that was largely co-localized with mitochondria, causing fragmentation, MMP disruption, and down-regulation of mitochondrial stability markers (Fig 4 and S3B Fig)