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MARKUP UGANDA: COFFEE AND COCOA VALUE CHAINS PROJECT The Market Access Upgrade Programme (MARKUP) is an initiative of the EAC Partner States funded by the EU and aims at addressing both supply side and market access constraints of some of the key export-oriented sectors, with particular focuses on exports to the EU and ACP markets

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It is caused by repeated amplification of the CAG trinucleotide in the huntingtin (Htt) gene on the short arm of chromosome 4, which leads to a prolonged polyglutamine stretch at the N-terminus of the protein

It helps regulate appetite centers in the brain, slows gastric emptying, and reduces post-meal glucagon release