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Substituted alkyl refers to an alkyl group having from 1 to 5, preferably 1 to 3, or more preferably 1 to 2 substituents selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, aminocarbonylamino, acyloxy, amino, substituted amino, the substituted alkyl groups include halogenated alkyl groups and particularly halogenated methyl groups such as trifluoromethyl, difluromethyl, fluoromethyl and the like

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Psychiatry Clin Neurosci 67(7):483492 Rosales-Corral S, Hernndez L, Gallegos M (2015) Cannabinoids in neuroinflammation, oxidative stress and neuro excitotoxicity