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Phytochemicals in cancer treatment: From preclinical studies to clinical practice

albicans may also colonize existing pre-malignant lesions and promote the progression of cancer by mediating the synthesis of the potent carcinogen, N -nitroso benzyl methylamine, from the precursors, N - benzyl methylamine and nitrite, at the neutral pH of the oral cavity [52]

Nov 2013;29(6):673-9

Disulfiram metabolites, including diethyldithiocarbamate (DDC), carbon disulfide (CS2), S-methyl N,N-diethylthiocarbamate sulfoxide (DETC-sulfoxide), S-methyl N,N-diethylthiocarbamate sulfone (DETC-sulfone), diethylthiomethylcarbamate, S-methyl-DDC, methyl diethylthiocarbamate sulfoxide, and methyl diethylthiocarbamate sulfone, play a crucial role in its pharmacological effects (PharmGKB, 2023)