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10.3389/fimmu.2025.1722777 27 ChengD.ShamiG

The main pathological hallmark of PD is the degeneration of dopaminergic neurons in the substantia nigra, resulting in dopamine deficiency and subsequent motor symptoms like bradykinesia, rigidity, and tremors [2]

doi: 10.1039/D2BM01915A 21 LanY.ZhouJ.XuK

NM_002084.3), in which the codons for Cys-12 (TGC), Cys-81 (TGC) and Cys-136 (TGT) were replaced with the codons for Ser (TCG) and the codon for Sec-53 (TGA) was changed to Cys codon (TGC)