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Horm Res 48 (Suppl 5): S105S110 Rudling M et al

rxlist.com (Ranexa ) Keywords Related to Antianginal Drugs Dipyridamole Trade Name: Persantine Drug Class: vasodilator, platelet inhibitor Mechanism of Action: Antiplatelet: inhibits platelet function by a combination of: inhibitor of phosphodiesterase type 3 prevents breakdown of cAMP increases cytoplasmic cAMP which lowers intracellular calcium levels inside platelets elevation of intracellular calcium is the major driving force to cause conformational change and degranulation of platelets, resulting in platelet aggregation