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Glutamine supplementation and deprivation: effect on artificially reared rat small intestinal morphology

Implementing tiered biomarker panels beginning with rapid first-tier plasma lactate and -hydroxybutyrate assays for acute triage, followed by second-tier CSF and metabolomic profiling for non-responders, enables precision therapy matching

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Pharmacokinetic analysis revealed it to be orally active with significantly increased metabolic stability, exhibiting a plasma half-life of 335.5 minutes, allowing for prolonged systemic availability [2]