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The apparent dispensability of gloA for the growth of Salmonella on glucose may reflect redundant mechanisms at this step of the methylglyoxal pathway

this finding may indicate that ascorbate can also function as an allosteric modulator of the OPR, which would be consistent with the fact that it shares some common structural binding motifs with opioid compounds [66,67,68] as well as shared GPCR enhancement [49,50,51,52,58,59,60,61,62,63,65,69,70,71,72,73,74,75,76,77]

Sun, X., Berger, R.S., Heinrich, P., Marchiq, I., Pouyssegur, J., Renner, K., Oefner, P.J., and Dettmer, K., Metabolites , 2020, vol

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