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Both cyanocobalamin and other forms of cobalamin can trigger these reactions, and the risk appears higher with parenteral (injection) administration compared to oral supplementation Khatrawi2022Sajan2023Ullah2018+1 MORE

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In agreement with these latter results, the work of Majors et al (1997) showed that a relatively low concentration of homocysteine (50 to 300 mol/L) stimulates collagen production in rabbit aortic smooth muscle cells that may favor extracellular matrix component accumulation in intimal lesions