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Clinical observations report density increases of 20 to 30 percent after three to six months of consistent topical use

Abnormal activation of the PI3K/AKT/mTOR-SREBP1c pathway up-regulates key lipid production genes, including fatty acid transporter (FATP1/2), acetyl-CoA carboxylase (ACC), fatty acid synthase (FASN) and stearoyl-CoA desaturase 1 (SCD1), thereby promoting the synthesis, invasion and transfer of new lipids [53]

The previous literature indicated that AST can ameliorate ferroptosis in acute lung injury and osteoarthritis patients (Luo et al., 2022