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10.1016/j.jtemb.2019.126418 237 SkjrringeT.BurkhartA.JohnsenK

MGMT promoter hypomethylation resulted in the abnormal expression in gene level, which reduced its ability to repair damaged genes, further exacerbating the stability of the chromosomes

Aging is commonly associated with gut dysbiosis, marked by reduced microbial diversity and a decline in beneficial bacterial populations, which has been linked to cognitive decline and increased frailty (Claesson et al., 2012