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Animals received the following treatments for 12 days: 0.9% saline, 100 ng/kg or 10 g/kg BPC 157

Microglial and astrocytic proteins are preferentially elevated in the GCLC-KO mouse brain To uncover mechanisms leading to brain atrophy in GCLC-KO mice, we next performed a comprehensive analysis of protein expression by Liquid Chromatography-Mass spectrometry (LCMS) analysis using brain samples from 4-month-old GCLC-KO mice (Fig

We used this information to design a tailored affinity maturation library for R023, aiming to decrease its dissociation rate from soto-p 7 /A*03 and A*11 while maintaining minimal competition with free sotorasib