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Upon NLRP3 activation, apoptosis-associated speck-like protein containing a CARD (ASC) and the precursor of pro-caspase-1 are recruited to form an inflammasome complex (Jiang et al., 2023b), subsequently triggering the self-cleavage of pro-caspase-1 to form active caspase-1 (Meng et al., 2023b)

In vivo biological tests utilized C57BL/6 mice subjected to a subacute PD model induced by daily intravenous administration of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (40 mg/kg) for seven days

One way that an urban hospital can reclassify as rural under 412.103 (specifically, 412.103(a)(3)) is if the hospital would qualify as a rural referral center (RRC) as set forth in 412.96, or as an SCH as set forth in 412.92, if the hospital were located in a rural area

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