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doi: 10.1097/MPA.0000000000000414 174 Bezmin AbadiAT

By contrast, xenoestrogens commonly found in polymers of plastic polycarbonates, such as mineral water bottles and lacquer coating in food cans, can act as endocrine disruptors that significantly alter estrogen-mediated signaling pathways (Brotons et al., 1995

The LA/Ao ratio was devised by medical researchers in a 1974 study of humans, based upon the assumption that humans' normal sized LAs and Aos are proportional to each other, and so the LA/Ao ratio can indicate a reference range of normal sized human left atriums and degrees of left atrial enlargement

The role of exact exchange