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Crucially, IONPs have been found to induce cell death via lysosomal leakage when a magnetic field was introduced as an external stimulus (Figure 1a) (Sanchez et al., 2014

It should be noted that the SC formulation for the preclinical and clinical bridging studies can theoretically be supplied in a vial presentation and does not have to be supplied in the commercial SC injection device, assuming that the stability of the SC formulation in the vial is comparable to the stability in a syringe or cartridge configuration