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doi: 10.2174/1381612823666170111100531 10

ALK5 knockdown and its downstream pathway protected LUHMES cells from aSyn-induced toxicity To verify that the knockdown of ALK5 protected against aSyn-induced toxicity, we first validated whether the siPOOL siRNA against ALK5 could effectively and specifically reduce ALK5 mRNA expression

Standard treatmentsincluding surgical resection, radiotherapy, chemotherapy with Temozolomide (TMZ), 8 and tumor treatment fields (TTF) therapy 9 offer only marginal survival benefits