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10.1016/S1570-0232(03)00399-4 Summary Keywords acetaminophen, reactive metabolite, covalent binding, glutathione S -transferase, bottom-up proteomics, data-dependent acquisition, high-resolution tandem mass spectrometry, multiple reaction monitoring Citation Geib T, Lento C, Wilson DJ and Sleno L (2019) Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S -Transferases

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That means if you're trying to get all your B12 from food, make sure to aim to consume at least twice the recommended daily intake, or at least 6 mcg