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Lapatinib is commonly used in the treatment of HER2 positive breast cancer but is prone to recurrence due to drug resistance (Yuan et al., 2023

Indeed, gp96 can be re-presented by antigen presenting cells via cell surface receptor CD91, whereby the chaperone and its bound peptide are endocytosed

These bacteria live with us our whole lives

A hypoxic microenvironment results from the abnormal vasculature that impairs blood flow, thus impedes the supply of oxygen to the tumor tissue

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