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[43] reported that endothelial dysfunction appears not only in the end stage but also as an early feature of COPD

6), making it harder for the DA system with the high-resolution model to constrain the error perturbation compared to the DA system using the low-resolution model

To date, the best-known COX-1- and COX-2-targeted inhibitors are nonsteroidal anti-inflammatory drugs (NSAIDS), such as aspirin, celecoxib, and rofecoxib, which are used to relieve pain, fever, and inflammation with additional benefits of treating or preventing heart attacks, strokes, or chest pain

However, strategies that promote gpx-1 activity should be used with caution and fully evaluated before clinical acceptance