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Although this notion was supported by studies in Apoe / (365) and ApoE*3Leiden mice (366) in which fenofibrate reduced atherosclerosis, a multinational trial including over 10,000 patients with CVD, demonstrated that pemafibrate was not associated with lower incidence of cardiovascular events although NAFLD incidence was reduced (153)

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Results indicated significant variability in extract activity by grape origin and cultivar, although no specific correlation emerged when averaged across samples

Otherwise low toxicity water-soluble