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The activation of AMP-activated protein kinase can result in BM loss and increase energy metabolism by decreasing gluconeogenesis and fatty acid production and boosting catabolism (Reference Long and Zierath124)

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Door zijn werking op melanocortine-systemen is Melanotan II een bekend onderzoeksobject binnen experimentele studies op het gebied van metabolisme, neurologische processen en pigmentatie-gerelateerde mechanismen