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Intracellular succinate can also be exported to the extracellular space and enter the circulatory system, such as in skeletal muscle cells, where succinate can be secreted into the extracellular milieu by MCT1 and bind to the succinate receptor-1 (SUCNR-1) on non-myofibrillar resident cells, activating downstream signaling pathways like ERK1/2 and PI3K-AKT [75, 76]

Statistical Analyses Statistical analyses of cell experiments were conducted by using the GraphPad Prism (GraphPad Software, version 9, San Diego, CA)

Salutary effect of gastric pentadecapeptide BPC 157 in two different stress urinary incontinence models in female rats

Post-surgical use supports the actual wound repair process