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johnsonii supplementation (Nadatani et al., 2019)

It has been associated with increased BDNF and TrkB signaling in rodent brain studies, modulation of dopamine and serotonin systems, and gene-expression changes in ischemia models

Metabolite extraction To extract intracellular metabolites, cells were washed three times with dPBS and metabolites were extracted with cold LCMS grade 80:20 methanol/H 2 O (v/v)

By integrating large-scale QTL/GWAS evidence with transcriptome-guided prioritisation and haplotype analysis, this work provides a systems-level synthesis of the genetic architecture underlying Fe stress adaptation in rice