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Description

Consequently, patients are frequently diagnosed only at advanced stages and are often referred directly to palliative care (Taylor et al., 2019)

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Teskey G, et al

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This post-translational modification is now recognised as a major mechanism of redox-regulated cell signalling, controlling the activity of transcription factors, kinases, phosphatases, and metabolic enzymes in response to the intracellular redox environment

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Conversely, acetylation and succinylation lead to the inactivation of the enzyme and sirtuins can remove these PTMs

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