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T cells are considered the main contributor to the onset and progression of pSS

In a finding from by Ohm group, VEGF inhibited the formation of T cells from early hematopoietic progenitor cells, suggesting that VEGF may have an immunosuppressive effect in malignancies [41]

ACTL6A, a member of SWI/SNF complex, has been reported to be involved in various cancers, including squamous cell carcinoma 11,14,52 , colon cancer 12 , osteosarcoma 53 , glioma 10,54 , and hepatocellular carcinoma 13

The in vivo imaging was performed by an AMI HTX (Spectral Instruments Imaging, Tucson, AZ, USA) with ex = 640 nm and em = 690 nm