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Rare variant burden analysis within enhancers identifies CAV1 as an ALS risk gene

By incorporating modifications such as the substitution of Arginine for Glutamic Acid at the third position and extending the peptides N-terminus, IGF-1 LR3 exhibits an enhanced biological activity and a significantly prolonged half-life of approximately 20-30 hours in the human body

Nuclear receptor coactivator 4 (NCOA4) is a widely expressed intracellular protein that can mediate ferritinophagy to control the release and storage of iron within cells