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So, what Qiufu Ma's lab found was that if electroacupuncture is provided to the abdomen, to the stomach area, it creates activation of what are called the sympathetic ganglia, and the activation of these neurons involves noradrenaline and something called NPY, neuropeptide Y

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Changes in the levels of SPM secreted by PBMC were positively correlated to changes in plasma transthyretin, and to cognitive changes as well (115)

ADGRA1 also known as GPR123 negatively regulates energy expenditure and thermogenesis by acting through the sympathetic nervous system and the HypothalamicPituitaryThyroid (HPT) axis