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Tirzepatide acts directly on the brain to reduce cravings and increase feelings of fullness

In a whole-transcriptome analysis, hsa_circ_0085121 (circRNF19A) exhibited overexpression in CaP cells and samples, and encoded a 490 amino acid polypeptide, which was designated circRNF19A-490aa

Derosa G, Maffioli P, Salvadeo SA, Ferrari I, Gravina A, Mereu R, et al

The Schirmer test, fluorescein sodium staining, HE staining and TUNEL staining were used to detect the tear secretion, corneal injury, histopathological changes of the cornea and lacrimal gland, and the apoptosis rate of cornea epithelial cells after 3 days of the administration