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Lung Inflammation in alpha-1-antitrypsin deficient individuals with normal lung function

10.1002/tox.22075 47 HicksonL

Human cell fractionation, western blot, and co-IP The transfected cells were harvested and washed with PBS

This is because Mfn2 overexpression can mediate smooth muscle cell apoptosis by inhibiting protein kinase B (Akt) signaling and activating mitochondrial apoptosis (185)