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Pettine et al 60,61 conducted a prospective nonrandomized cohort study including 26 patients affected by chronic LBP unresponsive to conservative treatment with a modified Pfirrmann score of 47 at MRI

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He referred us to the protocol Defining informative priors for ensemble modeling in systems biology (Tsigkinopoulou et al., 2018), from which we followed the basic steps to produce log-normal distributions for each of the kcat and Km values