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Since secondary infections can develop, its generally helpful to start antibiotics right away, in order to head off severe issues such as pneumonia

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years

It is worth noting that flavonoids encompass many compounds beyond those detailed here