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Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and tumor regression

High-resolution blood flow velocity measurements in the human finger

Consistent with this, increases in levels of p16 (CDKN2A) (1.23 fold) and p21 (CDKN1A) (1.48 fold), which are often augmented in senescent cells 48,49,50 , were also detected in chronically-irradiated cells, but do not appear in Fig

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