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[DOI] [PubMed] [Google Scholar] 20.Jandric I, Vrcic H, Jandric Balen M, et al

Clinical trials will be essential to validate these strategies, particularly in comparison with existing treatments like pirfenidone and nintedanib, to assess the added benefits of macrophage-targeted interventions

The cumulative antioxidant activity could be very high with the reactivation of the carboxylic groups (e.g., glutathione or enzymes)

Subcutaneous injection is the standard administration route for MOTS-c due to poor oral bioavailability peptide bonds are rapidly degraded by gastrointestinal proteases, significantly reducing systemic absorption