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3.1.3 Enzymes, surface molecules and antioxidant systems After SCI, microglia switch on the NLRP3-caspase-1GSDMD axis, causing pyroptotic rupture and a surge of IL-1/IL-18 that fuels secondary tissue loss

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Kavanagh JJ, Spriggs D, Bookman M, Ozols R, Gershenson DM, Han J, Lewis L, Brown GL, Dombrowski J, Maack C, Macpherson J, Lane A, Woodrow P and Henner WD